General Security Policy Administration
In the .NET Framework version 4, the common language runtime (CLR) is moving away from providing security policy for computers. Microsoft is recommending the use of Windows Software Restriction Policies as a replacement for CLR security policy. The information in this topic applies to the .NET Framework version 3.5 and earlier; it does not apply to version 4.0 and later. For more information about this and other changes, see Security Changes in the .NET Framework 4.
This section provides a set of guidelines that you can use to help administrate policy for your machine or enterprise. This information is meant to help you decide when to perform administrative tasks and what consequences these decisions have. For information on using tools to perform specific tasks see Security Policy Configuration.