Error: Mixed-mode debugging for x64 processes is supported only when using Microsoft .NET Framework 4 or greater
Visual Studio 2015
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The latest version of this topic can be found at Error: Mixed-mode debugging for x64 processes is supported only when using Microsoft .NET Framework 4 or greater.
To debug mixed native and managed code in a 64-bit process, you must have .NET Framework version 4. Mixed-mode debugging of 64-bit processes with .NET Framework versions earlier than 4 is not supported.
To correct this error
Perform one of the following steps:
Upgrade your .NET Framework to version 4.
Build a 32-bit version of your application for debugging.
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