Save a project or document
To save the active document
On the File menu, click Save (CTRL+S).
To save all documents in a project
On the File menu, click Save All (CTRL+SHIFT+S).
If you have any documents open for editing in Microsoft Visual Studio 2010 , they will not be updated in the Visual Studio 2010 window when you use the Save All command in Microsoft Expression Blend. However, the next time that you switch to your Visual Studio 2010 window, Visual Studio will display a prompt asking if you want to synchronize the changes that you made in Microsoft Expression Blend.