The setting in the machine configuration file is the default for all .NET Framework applications. The application configuration file setting overrides the machine configuration file setting.
If your application is single-threaded and involves heavy user interaction, leave concurrent garbage collection enabled to minimize the application's pause time to perform garbage collection. If your application is an ASP.NET server application you do not need to alter the default value of the gcConcurrent element.
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Concurrent garbage collection is not supported in applications running the WOW64 x86 emulator on 64-bit systems that implement the Intel Itanium architecture (formerly called IA-64). For more information about using WOW64 on 64-bit Windows systems, see Running 32-bit Applications
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