Protected Sub PreferredCheckBox_CheckedChanged(ByVal sender As Object, ByVal e As EventArgs) 

  ' Gets the CheckBox object that fired the event.
  Dim chkBox As CheckBox = CType(sender, CheckBox)

  ' Gets the item that contains the CheckBox object. 
  Dim item As ListViewDataItem = CType(chkBox.Parent.Parent, ListViewDataItem)

  ' Update the database with the changes.
  VendorsListView.UpdateItem(item.DisplayIndex, False)    

End Sub

protected void PreferredCheckBox_CheckedChanged(object sender, EventArgs e)
{
  // Gets the CheckBox object that fired the event.
  CheckBox chkBox = (CheckBox) sender;

  // Gets the item that contains the CheckBox object. 
  ListViewDataItem item = (ListViewDataItem) chkBox.Parent.Parent;

  // Update the database with the changes.
  VendorsListView.UpdateItem(item.DisplayIndex, false);
}