When AutoEventWireup is true, ASP.NET does not require that you explicitly bind event handlers to page events, such as Load or Init. Instead, handlers are automatically bound to events at run time based on their name and signature. For each event, ASP.NET searches for a method that is named according to the pattern Page_eventname, such asPage_Load or Page_Init. ASP.NET checks first for an overload that has the typical event-handler signature (Object and EventArgs). If an event handler with this signature is not found, ASP.NET checks for an overload that has no parameters.
When AutoEventWireup is false, you must explicitly bind event handlers to events. In that case, the method names do not have to follow a pattern.
The default value is true if AutoEventWireup is not specified in the @ Page directive. Visual Studio automatically includes the attribute when it creates code-behind files. For ASP.NET pages written in C#, Visual Studio sets the value to true. For Visual Basic, Visual Studio sets the value to false because handlers are bound to events by using the Handles keyword, which is inserted automatically by Visual Studio when it generates an event handler. If you set AutoEventWireup to true, you can omit (or remove) the Handles keyword.
Do not set AutoEventWireup to true if performance is a key consideration. When automatic event wireup is enabled, ASP.NET must make between 15 and 30 tries to match events with methods.
Note the following about binding event handlers to events:
If you set AutoEventWireup to true, make sure that you do not also manually attach page event handlers to events. If you do, handlers might be called more than one time.
Automatic binding is performed only for page events, not for events for controls on the page.
As an alternative to binding events to handlers, you can override the Oneventname methods of the page or of controls.